Physician Using App on iPad

What

Stressing Wisely is a scenario-based tool for clinicians to understand appropriateness of cardiac testing, including exercise treadmill stress, exercise SPECT stress, pharmacologic SPECT stress, exercise stress echo, pharmacologic stress echo, pharmacologic PET stress, pharmacologic stress MRI, coronary CTA, coronary calcium scoring, and cardiac catheterization, or no testing.

Stressing Wisely harmonizes and expands all published Appropriate Use Criteria (AUC), using inputs of patient-specific characteristics to map recommendations to specific AUC scenarios and guidelines, including references.

Why

There is high variability in the use of cardiac testing.

Appropriate use of cardiac testing may reduce unnecessary radiation exposure, patient risk, and adverse economic impact to patients and society.

AUCs are challenging to use in practice due to the vast number of clinical scenarios and the multi-modality nature of stress imaging.

Patient at CT Scanner
Patient at CT Scanner

Aims

  1. Harmonize all AUC documents and documents regarding contraindications in existence for stress imaging
  2. Develop a rules-based imputation for non-specified scenarios
  3. Create an easy-to-access graphical user interface (GUI) to assist clinicians in choosing appropriate cardiac imaging
  4. Provide prompt AUC feedback supported by references and/or rules-based clinical reasoning

Which

Stressing Wisely harmonizes:

  • 2023 ACC/AHA/ASE/ASNC/ ASPC/HFSA/HRS/SCAI/ SCCT/SCMR/STS Multimodality Appropriate Use Criteria for the Detection and Risk Assessment of Chronic Coronary Disease (Winchester et al. 2023)
  • 2020 SNMMI/ACC/ASNC/CCS/ CSCNCTI/SCCT/AHA/ ACP/EANM Appropriate Use Criteria for PET Myocardial Perfusion Imaging (Schindler et al. 2020)
  • 2020 SCMR Standardized cardiovascular magnetic resonance imaging protocols (Kramer et al. 2020)
  • 2019 ASE Guidelines for Performance, Interpretation, and Application of Stress Echocardiography in Ischemic Heart Disease (Pellikka et al. 2020)
  • 2014 ACCF/AHA/ASE/ASNC/ HFSA/HRS/SCAI/SCCT/ SCMR/STS Multimodality Appropriate Use Criteria for the Detection and Risk Assessment of Stable Ischemic Heart Disease (Wolk et al. 2014)
Filling of Red Yellow Green Scenario Ratings

How

All clinical scenarios from these guidelines and appropriateness ratings were reviewed and inputted into comprehensive matrices consisting of feature-scenario keys, scenario-rating keys, and rating-justification keys.

Recommendations about appropriateness were based on interweaving of the clinical scenarios, published AUC, modality-specific absolute contraindications, and modality-specific relative contraindications.

Specific decision rules for Stressing Wisely recommendations were developed to expand and cover scenarios not specifically addressed by current AUCs.

The application was coded using R, Shiny, PHP, MySQL, CSS, HTML, Bootstrap, and JS.

References

Our Team

Team Member 1

Ruey
Hu
MD, MPH

Cardiology Fellow
Team Leader

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Team Member 1

Camila
Trejo-Paredes
MD

Cardiology Fellow

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Team Member 1

Karo
Esin
MD

Cardiology Fellow

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Team Member 1

Marah
Maayah
BS

Medical Student

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Catherine
Wright
MD

Cardiology Fellow

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Attila
Feher
MD, PhD

Cardiac Imaging Faculty

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Team Member 1

Edward
Miller
MD, PhD

Cardiac Imaging Faculty

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